Is the liver really that fragile?

For the liver, people always have such doubts

Why didn’t you feel any pain?
liver cancer? Or late?
Is the liver really that fragile?

Liver
It is the largest digestive organ of the human body.

secretion and excretion of bile
Promote digestion and absorption in the small intestine
Metabolism, detoxification, hematopoiesis and other functions
Has a strong immune function

Even if the liver is so powerful
But it can’t escape the invasion of tumor
And most [liver cancer] is found in the middle and late stage.

According to the latest global cancer burden data for 2020 released by the International Agency for Research on Cancer (IARC) of the World Health Organization: an estimated 900000 people worldwide have been diagnosed with liver cancer, and about 830000 people die from liver cancer. For every 100000 people, there are 9.5 new cases of liver cancer and 8.7 deaths. Liver cancer ranks sixth among the most common cancers.
The liver has a strong compensatory reserve
Can maintain the normal functioning of the human body
No nerves in the liver
You won’t feel the pain
Primary liver cancer without obvious signs
until after the liver can’t function properly
Symptoms will gradually appear
Thus diagnosed.

With the wide application of alpha-fetoglobin (AFP) detection and the progress of various localization methods, the detection of 1~2cm small liver cancer has made people have a new understanding of the natural course of liver cancer. According to the new concept of natural course of liver cancer proposed by Tang Zhaoyou of Shanghai Medical University, the natural course of liver cancer can be divided into four stages:

• First, the early subclinical phase
  The diagnosis of subclinical liver cancer is established by precancerous cells, without any symptoms, and imaging is difficult to find.
• Second, the subclinical phase
  Patients with subclinical liver cancer at this stage have no symptoms and signs, and the diagnosis mainly depends on the detection of AFP and B- type ultrasound, CT examination and so on. This stage of the tumor is small, surgical resection of the opportunity.
• Third, mid-term
  From the appearance of symptoms and signs to the appearance of jaundice, ascites or distant metastasis, about 4 months. During this period, the vast majority of examinations such as enzymology, liver function and radionuclide scanning were abnormal.
• Fourth, late
  Jaundice, ascites, distant metastasis to death, the course of about 2 months.

Drinking as an “accomplice 〞…
Drinking can lead to alcoholic fatty liver, alcoholic hepatitis, alcoholic cirrhosis and other chronic liver diseases. In China, it seems that wine is indispensable at every table. Whether it is like or forced, in order to maintain the “network”, wine is a link that the Chinese cannot bypass.

aflatoxin
According to the epidemiological investigation, it is found that there are different degrees of aflatoxin pollution in the food consumed by residents in the high incidence area of liver cancer.

Hepatitis A, B and C virus infection
Alcoholics
transitional drug abusers
patients with viral hepatitis and diabetes mellitus
Family history of liver cancer

Although the malignant degree of liver cancer is high, early detection, early diagnosis and early treatment can bring ideal curative effect

The abnormality of these blood routine indexes in physical examination may be due to liver problems.

Transaminase index Serum protein index Bilirubin index

• Transaminases are found in the liver, heart, muscle and kidney cells, most frequently in liver cells. Generally, acute and chronic viral hepatitis is mainly caused by elevated alanine aminotransferase, while alcoholic liver injury is caused by elevated aspartate aminotransferase.
• Albumin index is synthesized by the liver, it can directly reflect the synthesis of liver cells. The index is elevated, which may be chronic hepatitis, alcoholic liver or liver cirrhosis and other liver diseases.
• Bilirubin index is the main index and basis for judging jaundice clinically. The type of jaundice can be determined according to the determination of direct bilirubin and indirect bilirubin.

Liver cancer is mostly found in liver disease follow-up or physical examination. Healthy people should be screened once a year. Regular screening should be carried out every 6 months after 35-40 years old ↓

Serum AFP test + liver ultrasonography

When it appears, you should immediately go to the hospital for follow-up, close observation, and strive to make an early diagnosis.
For high-risk groups

Abdominal color Doppler ultrasound + alpha-fetoprotein + liver function + hepatitis B and hepatitis C virus quantitative examination should be carried out every 3-6 months, and liver CT or MRI examination should be carried out if necessary.
Note: Liver cancer screening only screening abdominal color Doppler ultrasound to find liver cancer is not accurate, must be based on their own conditions combined with a number of liver examination diagnosis.